Mycobacterium tuberculosis does not inhibit NLRP1 and pyrin inflammasomes in human macrophages
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Mycobacterium tuberculosis (Mtb) has been known to evade host innate immunity by manipulating macrophage function. Interleukin-1β (IL-1β) is a cytokine secreted by macrophages as a consequence of inflammasome activation. Mtb can inhibit activation of the NLR... ...