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ClpC1-dependent iron homeostasis underlies mycobacterial defense against oxygen-driven Fenton reaction during reactivation

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The caseinolytic protease (Clp) system, which is highly conserved and essential for protein homeostasis in mycobacteria, comprises the ClpP1P2 proteolytic core and the essential ATPases ClpC1 and ClpX. While ClpX has a defined role in DNA replication, and some... ...