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Practical Enantioselective Approach to 3-Amino-2-Hydroxy Acids and Application to the Synthesis of Natural Products

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A practical approach to optically active erythro 3-amino-2-hydroxy acids has been developed and applied to the enantioselective synthesis of 3-phenylisoserine and naturally occurring 3-amino-2-hydroxy-6-methylheptanoic acid (AHMHA), a nonproteinogenic amino ac... ...