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EYA1 regulates CIITA phosphorylation to promote EYA1-CIITA-Runx2 complex formation and extracellular matrix integrity in osteoarthritis

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Background: Osteoarthritis (OA) involves progressive extracellular matrix (ECM) degradation in articular cartilage. We previously revealed that the m6A demethylase ALKBH5 stabilizes Runx2 mRNA in chondrocytes via YTHDF1, thereby ... ...