Unravelling the conformational dynamics of pathogenic mutations of apolipoprotein M: an integrative computational and molecular dynamics simulation approach
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Apolipoprotein M (ApoM), a sphingosine-1-phosphate (S1P) binding protein, is primarily synthesized in the liver and kidney. It is a key component of high-density lipoprotein (HDL) and plays a pivotal role in reverse cholesterol transport, vascular homeostasis ... ...
