QbD-Driven Rational Design of Vancomycin-Loaded Nanocubosome In situ Ocular Gels: Augmenting Precorneal Retention and Improving Anti-MRSA Keratitis Treatment
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Introduction: Vancomycin hydrochloride (VAN) is the treatment of choice for methicillin- resistant Staphylococcus aureus (MRSA) keratitis, but poor corneal penetration, epithelial toxicity, and the need for frequent dosing highli... ...
