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A High-Affinity NIR Fluorescent Probe for Aβ Oligomers Enables Theranostics Through Disrupting Membrane Interaction and Aggregation

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Amyloid-β (Aβ) oligomers serve as pivotal biomarkers and therapeutic targets in Alzheimer's disease (AD) due to their early emergence in pathogenesis and high level of neurotoxicity. In this work, we introduce a class of D-π-A amphiphilic fluorescent probe... ...