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Paclitaxel induced-mechanical hypersensitivity is associated with time-dependant pro-inflammatory galectin-3+ macrophages accumulation in the dorsal root ganglia

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Neuropathic pain is a dose-limiting side effect of chemotherapeutic agents such as paclitaxel, and it is unsuccessfully treated by available analgesics. Among the mechanisms underlying paclitaxel-induced neuropathic pain, neuroimmune interactions in the dorsal... ...