Maternal separation increases anxiety-like phenotypes, fear responses, and alters Bdnf methylation in a predator odor exposure model of early life adversity
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Early life adversity (ELA) can increase incidences of psychopathology later in life, partly through aberrant expression of the brain-derived neurotrophic factor (Bdnf) gene. One mechanism whereby ELA can alter Bdnf expression is through DNA methylation, typica... ...