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Lung cancer with EGFR PACC mutations: a practical review of available treatment options and novel therapies on the horizon

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Epidermal growth factor receptor (EGFR)-P-loop and αC-helix compressing (PACC) mutations are a recently proposed structural-functional category of mutations that represent more than 10% of all EGFR mutations in non-small cell lung cancer (NSCLC), including G7... ...