Carbonic anhydrase modulation in the tumor microenvironment: synergistic pathways with oncolytic viruses in gastrointestinal malignancies
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Gastrointestinal (GI) malignancies are leading causes of global cancer mortality, with advanced stages showing pronounced therapeutic resistance. A key driver of this aggression is the immunosuppressive and acidic tumor microenvironment (TME). This niche is cr... ...
