Nuclear receptor co-activator 4 interacts with RUVBL1/2 to maintain genome integrity through double-strand break repair
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DNA double-strand breaks (DSBs) are among the most cytotoxic forms of chromosomal lesions and are primarily repaired through homologous recombination (HR) or non-homologous end joining (NHEJ). The precise repair of DSBs via HR necessitates 5'-3' end resectio... ...
