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PKPD-Based Translational Modeling of Calaspargase Pegol Preclinical Activity in Hepatocellular Carcinoma

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Background and objective: Calaspargase pegol (CalPEG) is a PEGylated conjugate of L-Asparaginase (L-Asp) and an asparagine specific enzyme approved by the Food and Drug Administration (FDA) as a component of a multi-agent chemoth... ...