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Activation-induced cytidine deaminase promotes DNA demethylation and expression of the Ninjurin-2 gene

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Activation-induced cytidine deaminase (AID) is expressed in germinal center B cells and contributes to somatic hypermutation and isotype switching of immunoglobulins. AID is also reportedly expressed in colonic epithelial cells (CECs) during inflammation. Howe... ...