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Regioselective synthesis of 3-halo-2 H-chromenes via decarboxylative halogenation of oxygenated 3-carboxy-2 H-chromenes: Application to isoflavonoid synthesis

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A practical and regioselective method has been developed for 3-halo-2H-chromene synthesis via decarboxylative halogenation. These chromenes are key intermediates in synthesizing isoflavene derivatives and related bioactive compounds, including molecules of int... ...