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Low-Dose 125I-Irradiation Enhances PRC1-Targeted NIS-CAR-T Cell Cytotoxicity Against Breast Cancer Cells

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The efficacy of chimeric antigen receptor (CAR)-T therapy in solid tumors is limited by the immunosuppressive microenvironment and poor T-cell infiltration. Radiotherapy offers immunomodulatory potential, yet its synergy with CAR-T via targeted internal radion... ...