Dual Functional Potential of Poly(ADP-Ribose) Polymerase Inhibitor VIII: A Promising G-Quadruplex Stabilizer Targeting the Promoter of Oncogenes
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Poly(ADP-ribose) polymerases (PARPs) have emerged as pivotal therapeutic targets due to their essential function in DNA single-strand break repair, particularly in cancers with BRCA1/2 mutations. Although PARP inhibitors show promising clinical responses, thei... ...
