Integrated Multi-Omics Profiling Reveals Coordinated Transcriptional, Translational, and Metabolic Remodeling in IPF Fibroblasts
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Idiopathic pulmonary fibrosis (IPF) is characterized by persistent fibroblast activation and progressive extracellular matrix remodeling, leading to irreversible lung architectural distortion. Although high-throughput omics approaches have advanced understandi... ...