METTL3 loss exacerbates colitis via m6A-dependent Slc39a8 regulation and epithelial lineage depletion
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The intestinal epithelium maintains host-microbiota homeostasis, while inflammatory conditions, such as inflammatory bowel disease (IBD), induce pathological shifts in intestinal epithelial cell (IEC) subtypes. We unveil METTL3, an RNA m6A methyltransferase, a... ...
