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The C. elegans WASH complex supports epithelial polarity by promoting endosomal sorting of E-Cadherin

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Epithelial polarity requires polarized distribution of the apical adhesion complex that connects cells through the E-Cadherin transmembrane protein. E-Cadherin is intimately linked to the actin cytoskeleton through alpha catenin, which directly binds F-actin t... ...