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Portopulmonary hypertension and serum endothelin-1 levels in patients with liver cirrhosis

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A broad body of evidence has accrued, demonstrating the role of endothelin-1 (ET-1) in the pathophysiology of pulmonary arterial hypertension. Furthermore, the role of ET-1 as a causative pathophysiological mechanism of portopulmonary hypertension (POPH) has b... ...