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ERO1L induces macrophage infiltration to potentiate KrasG12D and inflammation-induced pancreatic tumorigenesis via oxidative protein folding of CCL2

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Pancreatitis is a significant risk factor for pancreatic cancer, with Kras mutations being the most common in this malignancy. Inflammation accelerates tumorigenesis driven by Kras mutations. However, the interactions between inflammation and Kras mutation in ... ...