Paclitaxel and triptolide impair MYC-driven cell cycle via suppressing chromatin reprogramming in ALDH1A3High pancreatic cancer
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Background and purpose: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy characterized by transcriptional heterogeneity and chemoresistance. We previously identified an aggressive PDAC subtype defined by high... ...