A miR-305-5p/Nerfin-1/Cyp18a1 cascade fine-tunes 20-hydroxyecdysone degradation to time pupariation in Drosophila
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Steroid hormone pulses provide critical temporal signals that synchronize developmental transitions, yet the mechanisms that restrain hormone clearance and preserve pulse timing remain unclear. Using Drosophila melanogaster metamorphosis, a process orchestrate... ...