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Integrative Single-Cell and Bulk Transcriptomic Analysis Defines a Molecular Stratification Strategy Based on Intra-Tumoral Heterogeneity in Acral Melanoma

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Acral melanoma (AM) is a rare subtype of melanoma with high malignancy. Although the transcriptional landscape of the tumor microenvironment (TME) in AM has been characterized, the heterogeneity of malignant cells and underlying molecular features remain to be... ...