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Peri-transplant molecular MRD monitoring by targeted NGS in patients with FLT3-ITD mutated acute myeloid leukemia

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Relapse is the predominant cause of treatment failure after allogeneic hematopoietic cell transplantation (allo-HCT) in FLT3-ITD-mutated AML. Although measurable residual disease (MRD) is increasingly used for risk stratification, optimal FLT3-ITD MRD assessme... ...