Novel (Z)-3-(2-(quinazolin-4-yloxy)phenyl)acrylates as potential EGFR inhibitors deriving from the renovation of coumarin skeletons: Design, synthesis, characterization and antineoplastic activity
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The inhibitors of epidermal growth factor receptor (EGFR) have emerged as one of fastest-growing medications that are widely utilized to control the spread and proliferation of malignant tumors. Based on the structural features of quinazoline-containing EGFR i... ...