Synergistic hepatotoxicity of azithromycin and acetaminophen involves liver X receptor α-mediated metabolic dysregulation and endoplasmic reticulum stress
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Coadministration of azithromycin (AZM) and acetaminophen (APAP) is associated with an increased risk of hepatotoxicity, the underlying mechanism for which remains unclear. Here, we demonstrate that combined AZM and APAP treatment induced liver injury in mice, ... ...
