Zasp52 in Drosophila melanogaster indirect flight muscles can serve as a model system to investigate the function of clinical variants causing myopathies
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The sarcomere is the basic contractile unit of muscle fibers, bordered by Z-discs. In Drosophila, Z-disc structure and maintenance rely on actinin and the Z band alternatively spliced PDZ-motif protein 52 (Zasp52), a member of the Alp/Enigma family. Zasp52 has... ...
