All-Hydrocarbon Stapling and Amino Acid Substitution-Modified Antimicrobial Peptide Feleucin-K3 Analogs Enhanced the Stability and Optimized the Therapeutic Index against Multidrug-Resistant Bacteria
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Our previous research found that the poor stability of the antimicrobial peptide Feleucin-K3 (FK3) had limited its transition into clinical application. Herein, we developed a series of FK3 derivatives stapled by all-hydrocarbon and thioether to enhance the st... ...
