The role of kir4.1/Kir5.1 in mediating the effect of angiotensin-II on Na-Cl-cotransporter
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Purpose of review: Angiotensin-II plays an important role in regulating thiazide-sensitive Na-Cl-cotransporter (NCC) encoded by Slc12A3. Moreover, inwardly-rectifying-K+ (Kir) channels 4.1/Kir5.1 encoded by Kcnj10 and Kcnj16 have... ...