Renal NHE3 is required to limit hypokalemia and metabolic acidosis during dietary potassium deficiency
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The sodium-hydrogen exchanger isoform 3 (NHE3) is a critical mediator of proximal tubule and thick ascending limb Na+ reabsorption and H+/NH4+ secretion, yet the physiological implications of its upregulation during low K+ intake remain poorly understood. We h... ...
