The hepatitis E virus capsid protein forms amyloid-like fibrils that sequester TANK-binding kinase 1 to dampen antiviral responses
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Hepatitis E virus (HEV) is the leading cause of viral hepatitis worldwide. We find that the HEV ORF2 capsid protein contains intrinsically disordered regions (IDRs) at its N terminus that promote condensate formation through liquid-liquid phase separation both... ...
