Bidirectional regulation by BACH2 coordinates systemic CXCR5- vs. CXCR5+ CD4+ T cell differentiation
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CD4+ T cells differentiate into T follicular helper (Tfh) and non-Tfh cells, helping regulate humoral and cellular responses. Here, we show that in robust CD4+ T cell responses, all early CXCR5+CD4+ T cells expressed CD25, and STAT5, which inhibits Tfh cell di... ...
