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Sigma-1 receptor promotes glycolysis in neuronal systems by suppressing GRIM19

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Sigma-1 receptor (S1R) is a Ca2+ sensitive, ligand-operated receptor chaperone protein present at the mitochondria-associated ER membrane. The relevance of S1R to glycolysis in neurons is not known. This study examines the impact of S1R on glycolysis, mitochon... ...