An Enzyme-Responsive Gd(III) MRI Probe for Visualizing β-Hexosaminidase A Activity
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We report the design, synthesis, and evaluation of HexA-Gd, a bioresponsive magnetic resonance imaging (MRI) contrast agent for the selective detection of β-hexosaminidase A (Hex-A) activity. The probe employs a self-immolative linker strategy that modulates ... ...
