HIV-1 BG505 SOSIP immunization induced B cell expansion targeting the 465-glycan hole, with neutralizing antibodies exhibiting distinct binding modes and mechanisms of virus inhibition
{{output}}
High serum neutralization following BG505 SOSIP.664 envelope trimer immunization was associated with protection against BG505.SHIV challenge in rhesus macaques in a previous study. In an animal that developed high titer, durable neutralization against a glycan... ...
