One-step cleavage and purification: a bifunctional IdeS-Protein A fusion protein for on-column generation of antibody fragments
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Conventional production of antibody fragments (e.g. Fab/F(ab')2, VHH/(VHH)2) involves sequential enzymatic cleavage and multi-step purification to remove Fc domains and residual enzymes, a process that is laborious and inefficient for small-scale workflows. T... ...
