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SUMO3/ RUNX1/ AIRE/ RCAN1 and DNMT3L/ DYRK1A/ Let-7c-5p/ VEGF axes: immune dysregulation and genetic susceptibility as pulmonary risk factors in Down syndrome

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This study investigated the cytokine profiles and expression patterns of chromosome 21 genes in Saudi Arabian children with Down syndrome (DS) to identify molecular drivers of immune dysregulation and pulmonary complications. This case-control study enrolled 1... ...