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Deterioration of Liver Fibrosis by ALR Deficiency is associated with reducing MICU1/2 Heterodimerization and Mitochondrial Ca2+ imbalance in Hepatic Stellate Cell

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Hepatic stellate cells (HSCs) activation is a pivotal event in the pathogenesis of liver fibrosis (LF). Mitochondrial calcium (mCa2+) dyshomeostasis is a known driver for HSCs activation. Although we previously demonstrated that augmenter of liver regeneration... ...