Interaction of venlafaxine and its major metabolite O-desmethylvenlafaxine with phosphatidylcholine bilayer
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Venlafaxine (VLX) and its active metabolite O-desmethylvenlafaxine (ODV) must partition into lipid membranes before reaching their membrane-embedded transporter targets. The principal active metabolite, ODV, differs from VLX by the removal of a methyl group an... ...
