Fluorescence readouts of KL4-induced changes in lipid order and fluidity in surfactant-like bilayers relevant to ARDS and COVID-19 lung injury
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KL4, a 21-residue mimetic of the C-terminus of surfactant protein B, is effective in treating infant respiratory distress syndrome (RDS). It works by reducing alveolar surface tension and improving oxygen exchange. Here, we use steady-state fluorescence measur... ...
