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Clinicopathological significance of methylthioadenosine phosphorylase (MTAP) expression loss in hepatobiliary tumors

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Backgrounds: Expression loss of methylthioadenosine phosphorylase (MTAP), a tumor suppressor gene often co-deleted with CDKN2A/B, is a useful diagnostic marker of malignant tumors, such as mesothelioma, and a potential therapeuti... ...