Resolution of Tryptophan Ethyl Ester by Forming Diastereomeric Salts With Di-p-Toluoyl-L-Tartaric Acid
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A resolution of racemic tryptophan ethyl ester (TrpEt) was performed using L-di-p-toluoyl tartaric acid (L-DTTA) as the resolving agent. Response surface methodology (RSM) was employed to systematically investigate the effects of solvent dosage, molar ratio of... ...