Photocontrolled immunotherapy: a BODIPY-caged MSA-2 for spatiotemporal activation of STING with visible light
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The STING pathway is a promising target for cancer immunotherapy, but systemic activation by small-molecule agonists can cause adverse effects. We report a visible light-activatable STING agonist, BODIPY-MSA-2, enabling precise, light-dependent uncaging and re... ...