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Globular oligomers as the building block units of the filamentous structure of E. coli small heat shock protein IbpA and their holding chaperone activity

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In E. coli, IbpA is a small heat-shock protein, which acts as molecular chaperone with only holdase activity. At normal temperature, IbpA monomers oligomerize to form filamentous structure of molecular weight in mega-Dalton range, whereas at higher temperature... ...