Guggulsterone as a Modulator of the Microbiota-Bile Acid-FXR Axis: Molecular Mechanisms and Therapeutic Potential in Metabolic Ageing
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Cholesterol biosynthesis and bile acid metabolism are tightly controlled by the Farnesoid X receptor (FXR), which integrates bile acid signaling with lipid, glucose, and inflammatory pathways to maintain metabolic homeostasis. Gut microbiota dysbiosis alters b... ...
