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Zinc silicate modulates bone substitute degradation following macrophage activation via the JAK/STAT pathway and expedites the initiation of bone repair: in vitro and in vivo studies

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Repairing segmental bone defects remains difficult because conventional bone substitutes rarely integrate immunomodulation with efficient tissue regeneration. To address this limitation, zinc silicate/collagen/hydroxyapatite (ZCH) composites were developed whe... ...