Plasma and Cerebrospinal Fluid Pharmacokinetics of Clazosentan and its Relationship to Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage
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Background: Clinical pharmacokinetic data on clazosentan, an endothelin receptor antagonist, after aneurysmal subarachnoid hemorrhage (SAH), particularly data on cerebrospinal fluid (CSF), remain limited. In this study, we evalua... ...
