DNA Hypomethylation in Pancreatic Cancer Tissues Before Treatment, Defined by KRAS-mutated Circulating Tumor DNA, is Associated With Poor Prognosis
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Objects: Aberrant hypomethylation of long interspersed nucleotide element-1 (LINE-1) and satellite alpha (SATa) in pancreatic cancer cells increases malignant potential. In addition, circulating tumor DNA (ctDNA) is likely to be ... ...